Products 1 – 13 of 13 Distraccion osteogenica mandibular en sindrome de Nager. Key words: Nager’s syndrome, postaxial acrofacial dysostosis, mandibular. References [1] Tosta E, Spina M. Distracción osteogénica mandibular para la 3. Period of activation-application of distraction forces. colocación de implantes. La distracción osteogénica es actualmente utilizada para el elongamiento tisular, quien fue tratado con distracción mandibular a través de corticotomías en.

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Distraction osteogenesis is a technique for induction of new bone formation between two segments of a bone that presents wide possibilities mandlbular use in Dentistry.

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However, the available information on this subject is still scarce. The aim of this article is to review the literature related to bone formation, mechanically induced by distraction osteogenesis, in order to supply subsidies the agreement of this process.

Distraction osteogenesis; Bony formation; Dentistry. The distraction osteogenesis DO is a method developed for induction of new tecidual formation between two segments of a bone for a slow and gradual force of traction Ilizarov, a; Ilizarov, b; Meyer et al. Some tissues besides bone have been observed to form under tension stress, including mucosa, skin, muscle, tendon, cartilage, blood vessels, and peripheral nerves Cohen et al. The DO application has modified the treatment form of the congenital and acquired craniofacial defects.

According to recent studies, reabsorption toothless alveolar rims or mandibular and maxilar atrophies caused by a syndrome can also be corrected successfully with this technique Jazrawi et al. In the distraction process, there are 3 fundamental sequential phases in which different biologic phenomena are produced.

These have been experimentally studied in bones of endochondral or intramembranous origin. Latency phase is the period between performance of osteotomy and start of the traction, during which soft callus is formed. Time periods usually applied range from 0 to 7 days and coincide with the initial events in the normal process of bone repair; Distraction phase is the period in which traction is applied to the transport bone fragment and the formation of new immature woven and parallel-fibered bone commences.

This phase usually lasts weeks, and the traction modifies the normal development of the regeneration process; and Consolidation phase is the period that allows the maturation and corticalization of the regenerated bone. In craniofacial bones, a week phase is recommended for children and a week phase for adults, although the appearance of bone with identical characteristics to those of the initial bone may take more than a year Cohen et al.

Once the distraction is ended, the central fibrous and osteoid areas ossify and gradually mineralize in a largely intramembranous manner in facial bones, becoming immature bone that will form remodeling areas for transformation into mature lamella bone.

In maxillary bones, the mandibbular is largely intramembranous, although foci of endochondral ossification have been reported by some authors. The DO technique presents wide possibilities of use in some areas of Dentistry, as Osteogenics, Orthodontics, Facial Orthopedic and also in the Oral Rehabilitation where one of the major problems is the alveolar bone loss, the support for protheses, implantations and adjacent soft tissues.

The aim of this article is to revise the literature related to bone formation, mechanically induced by Osteogenic Distraction, in order to supply subsidies for this process. In the century XIV, Guy de Chauliac was the first one to study the continuous traction for reduction of breakings.

The concept of osteotomies was established in the century XIX when Malgaine described the concept of the external setting in the treatment of patelares composed breakings McCarthy et al. The Osteogenic Distraction is a method developed for induction of new bone formation between two segments of a bone for a slow and gradual force of traction Campisi et al.

It can be classified in two basic types: The calotasis is being used more in the distraction osteogenesis in experimental models and clinical applications distfaccion the clinical difficulties associates to the first principle epiphyseal tissues fragility for the setting of traction mechanical systems and the new bone formation inhibition because the trauma generated for these instruments.


Ilizarova russian orthopedics doctor, started his perfectioning and applied the DO technique in the superior and inferior endochondral bones members for more than 35 years. It consisted in fixed bolts in the proximal distrraccion distal portion of the segments and joined for a telescope tube. A distraction mechanism was formed because the continuous and appropriate force was applied by a device McCarthy et al.

Other authors had followed this idea, but it was only in the decade of the 50’s that Ilizarov a, b promoted the extend bone by distraction osteogenesis having consistent and previsible results. Osteogeenica showed that the fibrous matrix in the prolongated area is capable to differentiate by itself in lamellar bone tissue. This fact occurred due to the gradual bone callus extend respected the capacity of vessels that nourish the region repair.

Since carried through of rhythmic and gradual form the bone extends is possible. Thus, the periosteum and endosteum osteogenesis capacity are related to the formation of a new bone matrix in parallel columns to the extend axis Querido, He established the so-called Ilizarov effects: Gradual traction of the tissues creates stress that activates tissue growth and regeneration law of tension-stress ; and the distraccipn and mass of the bone are influenced by the mechanical load and blood supply.

Ilizarov performed tibial distraction in dogs. He observed that a distraction rate of 0. With respect to the frequency of distraction, he recorded better outcomes when it was performed 60 times a day compared with 1 or 4 times a day. In other words, he defended the continuous application of tension.

He demonstrated that distraction was also produced transversally to the longitudinal axis of the bone, which is of relevance to the osteeogenica of the alveolar ridge.

Ilizarov a described 2 basic types of distraction: They are also described, respectively, as distraction epiphysiolysis fast traction: The concept of callotasis is of interest osteogenifa implant surgery, especially monofocal callotasis for the distracfion regeneration of tissues. When segmental defects are reconstructed, bifocal or trifocal distraction is used. This technique was only spread out when Ilizarov presented his studies in a Symposium occurred in New York in the year of a, b.

Ilizarov had already reported that the ideal frequency of distraction is continuous. In fact, mandibular elongation distractors have been designed for this purpose using hydraulic or spring wire mechanisms.

In clinical alveolar distraction studies, some authors attempted to approach this frequency by applying more than 1 distraction procedure per day, distributing the daily amount of distraction between distrxccion sessions of 0.

With the success, they proposed an intra-buccal distractors model for human, but it did not arrive to be used. These last ones, djstraccion to be more steady and malleable, made it difficult for the patients for being discomforted. They extend the ascending disrraccion of 4 children through an extra-buccal device having between 18 and 24mm of growth.

InMartin Chin related be the first author to carry out DO with intra-bucal apparatus in human for alveolar process growth Feichtinger et al. There has been little study of changes in the oral mucosa as a consequence of distraction. In a beagle mandibular elongation model. After distraction, atrophy of the epithelium was observed, with the disappearance of papillae and the loss of intercellular connections in granular and spinous layers, the formation of dilated capillaries was increased in the lamina propria, there was a mild inflammatory infiltrate, and the collagen fibers were distributed parallel to the distracciion vector.

At 2 weeks of consolidation, the mucosa began to show a more normal appearance: Conjunctive papillae began to appear, the epithelial thickness increased, and the cells recovered a normal architecture, although the osteogejica infiltrate and low thickness of the horny layer persisted.

At 8 weeks, the epithelium had a completely normal appearance, with no scars in any area. There mmandibular to be an initial stretching of the mucosa, which undergoes reorganization in response to this new spatial situation.

Msndibular, after a period of consolidation, there seems to be greater cell proliferation in the basal layer. With the technology and the materials used for the construction and manufacture of odontologics equipments and instruments advanced, more delicate distractor were done.

The use indications have grown for the most diverse types of bones deformities. A singular aspect of the distraction technique is the fact of regeneration be followed by a simultaneous expansion osteogeinca soft tissues, including vases, nerves, muscles, skin, mucosa, fascia, ligaments, cartilage and periosteum.


This adaption process of adjacent soft tissues provoked by tensions generated for the distraction forces is also known as histogenic distraction. More recently, DO has modified the treatment form of the congenital and acquired craniofaciais defects Altuna et al.

With the use of force vectors is possible to get a significant and steady bone remodel, in varied directions, without extensive surgical interventions Mehrara et al. Extra and intra bucal devices have been developed and used for this intention.

The effects of the distraction vector, ossteogenica distrator stabilization and the distraction intensity and frequency of the bone corn are variable that have been examined in some studies Kessler et al. DO have been used successfully in the surgeries of increase bone rim with diverse distraccionn. One of the important applications occurs in the extensive oral rehabilitations cases where unsatisfactory prosthetic reconstructions are frequent because jandibular the advanced alveolar rim loss and the difficulties in distraccioon it with enxertia.

The DO technique can be used in the rim increase that makes possible implantations arrangement and increase the possibility to get a better cantilever outline in the anodontics areas Gaggl et al. In the continuous DO an intramembranous bone ostrogenica occurs, while in the not continuous distraction process the regeneration follows a standard of chondroid ossification. With a continuous and lesser intensity force application the bone regeneration occurs in a faster speed and presents a lesser consolidation period Kessler et al.

The period of maintenance of the disjunction device as new bone stabilizing can be vary Forwood et al. Some distractors models are being currently produced and evaluated Grayson et al. Studies about compression, twist and shear forces application of the bone prolongated by osteogenesis distraction had been carried out. It was verified that after a period of stabilization mandibuoar 4 and 8 weeks, after the distraction forces application, the levels of regenerated bone compressibility and manibular already met normalized, although the levels of shear strenght, exactly after 8 weeks still remain reduced.

Until the present moment, the process that the mechanical forces created by the distraction osteogenesis are translated in biological signals able to induce osteogenesis in a perfectly coordinated way is still not clarified.

The technician resources of the distraction osteogenesis application proportionate benefits that represent an applicable reality in some areas of dentistry.

Surgically assisted rapid orthodontic lengthening of the maxilla in primates–a pilot study. Expression of bone morphogenetic proteins ostepgenica mandibular distraction osteogenesis.

Distraction osteogenesis of the human craniofacial skeleton: Applications for mandibular regrowth.

Biomechanics of mandibular distractor orientation: Evaluation of distraction implants for prosthetic treatment after vertical alveolar ridge distraction: Modification of the in vivo four-point loading model for studying mechanically induced bone distraccjon.

Healing process after alveolar ridge distraction in sheep. Development of a device for disrraccion delivery of distravcion to bone during distraction osteogenesis. Distraction osteogenesis of the mandible with a modified intraoral appliance: Differences in mandibular distraction osteogenesis after corticotomy and osteotomy. The tension-stress effect on the genesis and growth of tissues. The influence of stability of fixation and soft tissue preservation. The tension-stress effect on the genesis and growth of tissues: The influence of the rate and frequency of distraction.

Clinical application of the tension stress effect for limb lengthening. Bone and cartilage formation in an experimental model of distraction osteogenesis.

Distraccion osteogenica mandibular pdf |

The effects of magnitude and frequency of distraction forces on tissue regeneration in distraction osteogenesis of the mandible.

Correction of mandibular hypoplasia by means of bidirectional callus distraction. The role of chondrocytes in intramembranous and endochondral ossification during distraction osteogenesis in the distraccikn. The role of distraction osteogenesis in the reconstruction of the mandible in unilateral craniofacial microsomia. Lengthening the human mandible by gradual distraction.